(1) Grand Hôpital de l’Est Francilien (GHEF), Site de Meaux, Court séjour gériatrique, France. University of Oran 1- Ahmed Benbella, Department of Internal Medicine at the University Hospital , Oran 31000, Algeria ,

(2) Faculty of Life and Natural Science, Department of Biology, Djillali Liabes University of Sidi-Bel-Abbes. Laboratoire de Nutrition, Pathologie, Agro-Biotechnologie et Santé (Lab-NuPABS), Sidi-Bel-Abbes, 22000, Algeria